About Mandolin

Nearly all disease will become treatable in our lifetimes, and drug discovery is quickly becoming an engineering discipline. Mandolin is building the “last-mile” delivery infrastructure that gets cutting-edge biologics, cell, and gene therapies to patients faster. Our AI-powered knowledge-worker platform already serves leading infusion clinics, with payers and pharma next in line.

We’re backed by Greylock, SignalFire, Maverick, and founders of famous companies like Yahoo, and led by repeat and exited founders with a team hailing from some of the most technically impressive companies.

Why we need you

We’re post-product-market fit, growing fast, and entering a pivotal next chapter. As our first BizOps hire, you’ll have a front-row seat (and a direct hand) in building the future of our company—from internal systems to external strategy. This role is a launchpad into broader leadership depending on your interest.

As our first Business Operations Lead, you’ll be the connective tissue across the company—turning insight into action, chaos into structure, and vision into strategy. You’ll work directly with the CEO and leadership team on everything from internal operations to external go-to-market strategy, market intelligence, and investor communications.

This is a founding role for someone who wants to build not just the “how,” but also help shape the “why” and “where next.” If you're strategic, resourceful, and motivated by impact, we want to meet you.

What you’ll do

• Operational strategy: Analyze and refine how we operate—from team structure to process design to tooling.

• Market and competitive insight: Lead research to deepen our understanding of customer needs, competitors, and white space—turning findings into actionable priorities.

• Business model + pricing: Support development of new commercial models and refine existing pricing strategies with Product and Sales.

• OKRs and goal setting: Help the leadership team set and track company-wide priorities that align with both product and business objectives.

• Lead high-priority initiatives: Own complex, cross-functional projects—from customer operations to partner evaluations to new market assessments.

• Design scalable systems: Implement tools and workflows that improve company velocity and transparency (reporting, dashboards, documentation, etc.).

• Board & investor reporting: Own preparation of board decks, investor updates, and strategic narratives. Ensure we always know (and can tell) the story behind our numbers.

• Data + decision support: Build financial and operational models, generate insights, and guide decisions on hiring, GTM strategy, and expansion.

Must-have experience

• Have 7-10+ years of experience in strategy, BizOps, or consulting roles at high-growth startups, healthtech companies, or top-tier firms.

• Have worked in a 0→1 environment and helped build company-level strategy from the ground up.

• Are strategic and structured—you bring clarity to ambiguity, and frameworks to chaos.

• Think like a general manager: you’re commercially minded, analytical, and comfortable driving outcomes across functions.

• Are a crisp communicator—you can distill complexity and influence decisions from ICs to investors.

• Are equally comfortable in Google Sheets, boardrooms, Notion docs, and product meetings.

• Care deeply about impact and healthcare innovation.

Nice-to-haves

• Have experience in AI, healthcare, biotech, or regulated industries.